gene expression profiling of toll-like receptor 4 and 5 in peripheral blood mononuclear cells in rheumatic disorders: ankylosing spondylitis and rheumatoid arthritis
نویسندگان
چکیده
no abstract
منابع مشابه
Gene Expression Profiling of Toll-Like Receptor 4 and 5 in Peripheral Blood Mononuclear Cells in Rheumatic Disorders: Ankylosing Spondylitis and Rheumatoid Arthritis.
No Abstract.
متن کاملToll Like Receptor 2 and 4 Expression in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients
Background: Multiple sclerosis (MS) is a T cell mediated autoimmune disease with unknown etiology. Appropriate MS therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms. Ligation of TLR-2 and TLR-4 stimulates the production of several cytokines leading to CNS autoimmunity and neurodegenerative diseases. Objective: To find a relationship between M...
متن کاملtoll like receptor 2 and 4 expression in peripheral blood mononuclear cells of multiple sclerosis patients
background: multiple sclerosis (ms) is a t cell mediated autoimmune disease with unknown etiology. appropriate ms therapeutic strategies need thorough understanding of both disease etiology and pathogenesis mechanisms. ligation of tlr-2 and tlr-4 stimulates the production of several cytokines leading to cns autoimmunity and neurodegenerative diseases. objective: to find a relationship between m...
متن کاملWhole-blood gene expression profiling in ankylosing spondylitis shows upregulation of toll-like receptor 4 and 5.
OBJECTIVE to identify differentially expressed genes in peripheral blood cells (PBC) of patients with ankylosing spondylitis (AS) relative to healthy controls and controls with systemic inflammation. METHODS we investigated PBC samples of 16 patients with AS and 14 matched controls, in addition to systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) samples utilizing Illumina Human...
متن کاملMir-183 and FOXO1 gene expression changes in peripheral blood mononuclear cells of breast cancer patients
Background and Aim: Today, cancer is considered as a major health problem and affects the health of society. Breast cancer is the second leading cause of cancer death in women after lung cancer. According to epidemiological studies, cancer is the second most common cause of death after cardiovascular disease worldwide and the third leading cause of death after cardiovascular disease and acciden...
متن کاملIncreased Responsiveness to Toll-Like Receptor 4 Stimulation in Peripheral Blood Mononuclear Cells from Patients with Recent Onset Rheumatoid Arthritis
BACKGROUND Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, osteoarthrosis (OA), and healthy control (HC). METHODS PBMCs were stimulated with LPS, biglycan and ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۱۵، شماره ۱، صفحات ۸۷-۹۲
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023